Dual-modality fluorescence and full-field optical coherence microscopy for biomedical imaging applications
نویسندگان
چکیده
منابع مشابه
Dual-modality fluorescence and full-field optical coherence microscopy for biomedical imaging applications
Full-field optical coherence microscopy (FFOCM) is a high-resolution interferometric technique that is particularly attractive for biomedical imaging. Here we show that combining it with structured illumination fluorescence microscopy on one platform can increase its versatility since it enables co-localized registration of optically sectioned reflectance and fluorescence images. To demonstrate...
متن کاملFull-Field Optical Coherence Microscopy
Optical coherence tomography (OCT) is a well-established optical imaging technique with micrometer-scale resolution. OCT is based on low-coherence interferometry to measure the amplitude of light backscattered by the sample being imaged [1-4]. The most significant impact of OCT is in ophthalmology for in situ examination of the pathologic changes of the retina [5-8] and measurement of the dimen...
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Non-destructive optical imaging and probing techniques have found entrance and success in material sciences favoured by their non-invasive investigation character. X-ray computer tomography (CT) applied in a different size scale (e.g. as micro-CT and nano-CT [1]) is well established as a non-destructive technique in the field of material inspection. CT imaging delivers highly contrasted images ...
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Most pathological conditions elicit changes in the tissue optical response that may be interrogated by one or more optical imaging modalities. Any single modality typically only furnishes an incomplete picture of the tissue optical response, hence an approach that integrates complementary optical imaging modalities is needed for a more comprehensive non-destructive and minimally-invasive tissue...
متن کاملDual modality instrument for simultaneous optical coherence tomography imaging and fluorescence spectroscopy.
We develop a dual-modality device that combines the anatomical imaging capabilities of optical coherence tomography (OCT) with the functional capabilities of laser-induced fluorescence (LIF) spectroscopy. OCT provides cross-sectional images of tissue structure to a depth of up to 2 mm with approximately 10-microm resolution. LIF spectroscopy provides histochemical information in the form of emi...
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ژورنال
عنوان ژورنال: Biomedical Optics Express
سال: 2012
ISSN: 2156-7085,2156-7085
DOI: 10.1364/boe.3.000661